STS2 Enemy Bestiary

Complete database of 94 enemies in Slay the Spire 2:12 bosses,12 elites,70 normal monsters across all 4 acts. Click any enemy for detailed movesets, stats, and strategy tips.

👑 Bosses

(12 enemies)

⭐ Elites

(12 enemies)

Normal Monsters

(70 enemies)

Act 1: Overgrowth(21 enemies)

Assassin Raider

Assassin Raider

34-40 HP

Overgrowth

Applies Vulnerable before dealing heavy damage. Block the follow-up.

Axe Raider

Axe Raider

38-44 HP

Overgrowth

Pure damage dealer. No fancy mechanics, but hits hard.

Brute Raider

Brute Raider

50-60 HP

Overgrowth

High HP tank. Blocks frequently. Use burst damage windows.

Crossbow Raider

Crossbow Raider

32-38 HP

Overgrowth

Ranged attacker. Deals consistent damage every turn.

Cubex Construct

Cubex Construct

44-52 HP

Overgrowth

Shifts between attack and defense modes. Attack during defensive phases.

Eye With Teeth

Eye With Teeth

34-40 HP

Overgrowth

Multi-hit attacks that scale with Strength. Block is essential.

Flyconid

Flyconid

30-35 HP

Overgrowth

Summons minions to overwhelm you. Focus the Flyconid first.

Fogmog

Fogmog

40-48 HP

Overgrowth

Creates fog that reduces visibility. Damage ramps over time.

Fuzzy Wurm Crawler

Fuzzy Wurm Crawler

44-50 HP

Overgrowth

Deals moderate damage and applies debuffs. Prioritize after more dangerous enemies.

Inklet

Inklet

24-28 HP

Overgrowth

Low HP but can apply Blind (reduced accuracy). Kill quickly.

Leaf Slime (M)

Leaf Slime (M)

34-40 HP

Overgrowth

Stronger Slime variant with more HP and higher damage.

Leaf Slime (S)

Leaf Slime (S)

20-24 HP

Overgrowth

Frail debuff makes blocking harder. Focus down before debuffs stack.

Mawler

Mawler

48-56 HP

Overgrowth

High HP tank enemy. Deals heavy single-target damage.

Nibbit

Nibbit

32-38 HP

Overgrowth

Low damage but buffs itself over time. Kill quickly.

Shrinker Beetle

Shrinker Beetle

30-36 HP

Overgrowth

Reduces your max HP temporarily. Kill before HP reduction becomes permanent.

Slithering Strangler

Slithering Strangler

42-50 HP

Overgrowth

Applies debuffs and moderate damage. Target priority depends on team composition.

Snapping Jaxfruit

Snapping Jaxfruit

28-34 HP

Overgrowth

Thorns damage when attacked. Use multi-hit attacks carefully.

Tracker Raider

Tracker Raider

36-42 HP

Overgrowth

Marks you for increased damage from other enemies.

Twig Slime (M)

Twig Slime (M)

38-44 HP

Overgrowth

Stronger Twig Slime with more HP. Weak stacking is dangerous in longer fights.

Twig Slime (S)

Twig Slime (S)

22-26 HP

Overgrowth

Applies Weak debuff. Kill before debuff stacking cripples your offense.

Vine Shambler

Vine Shambler

50-60 HP

Overgrowth

Tanky enemy that entangles you. Kill before it locks down your entire strategy.

Act 2: Underdocks(16 enemies)

Act 3: Hive(17 enemies)

Act 4: Glory(16 enemies)